PAK2-ECE2 Fusion FISH Probe
The PAK2-ECE2 Fusion FISH Probe is used to confirm a fusion of the PAK2 and ECE2 genes. The fusion of the PAK2 and ECE2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAK2-ECE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-RERE | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-REOR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-REGO | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-REGR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-REAQ | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-ORRE | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-OROR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-ORGO | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GORE | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GOOR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GOGO | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GOGR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GRRE | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GROR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GRGO | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GRGR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-AQRE | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-AQOR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-AQGO | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-AQGR | 20 (40 μL) | 200 μL |
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| PAK2-ECE2-20-AQAQ | 20 (40 μL) | 200 μL |
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PAK2 Gene Summary
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
Gene Name: P21 (RAC1) Activated Kinase 2
Chromosome: CHR3: 196466727 -196559518
Locus: 3q29
ECE2 Gene Summary
The Endothelin Converting Enzyme 2 (ECE2) gene is located on chr3 :183967444-184010819 at 3q27.1.
Gene Name: Endothelin Converting Enzyme 2
Chromosome: CHR3: 183967444 -184010819
Locus: 3q27.1
Gene Diseases
The PAK2 ECE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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