PADI2-EXD3 Fusion FISH Probe
The PADI2-EXD3 Fusion FISH Probe is used to confirm a fusion of the PADI2 and EXD3 genes. The fusion of the PADI2 and EXD3 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PADI2-EXD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-RERE | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-REOR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-REGO | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-REGR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-REAQ | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-ORRE | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-OROR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-ORGO | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GORE | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GOOR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GOGO | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GOGR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GRRE | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GROR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GRGO | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GRGR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-AQRE | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-AQOR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-AQGO | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-AQGR | 20 (40 μL) | 200 μL |
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| PADI2-EXD3-20-AQAQ | 20 (40 μL) | 200 μL |
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PADI2 Gene Summary
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
Gene Name: Peptidyl Arginine Deiminase 2
Chromosome: CHR1: 17393255 -17445948
Locus: 1p36.13
EXD3 Gene Summary
The Exonuclease 3'-5' Domain Containing 3 (EXD3) gene is located on chr9 :140201347-140317714 at 9q34.3.
Gene Name: Exonuclease 3'-5' Domain Containing 3
Chromosome: CHR9: 140201347 -140317714
Locus: 9q34.3
Gene Diseases
The PADI2 EXD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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