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PACSIN2-CERK Fusion FISH Probe

The PACSIN2-CERK Fusion FISH Probe is used to confirm a fusion of the PACSIN2 and CERK genes. The fusion of the PACSIN2 and CERK genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PACSIN2-CERK-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PACSIN2-CERK-20-RERE 20 (40 μL) 200 μL
PACSIN2-CERK-20-REOR 20 (40 μL) 200 μL
PACSIN2-CERK-20-REGO 20 (40 μL) 200 μL
PACSIN2-CERK-20-REGR 20 (40 μL) 200 μL
PACSIN2-CERK-20-REAQ 20 (40 μL) 200 μL
PACSIN2-CERK-20-ORRE 20 (40 μL) 200 μL
PACSIN2-CERK-20-OROR 20 (40 μL) 200 μL
PACSIN2-CERK-20-ORGO 20 (40 μL) 200 μL
PACSIN2-CERK-20-ORAQ 20 (40 μL) 200 μL
PACSIN2-CERK-20-GORE 20 (40 μL) 200 μL
PACSIN2-CERK-20-GOOR 20 (40 μL) 200 μL
PACSIN2-CERK-20-GOGO 20 (40 μL) 200 μL
PACSIN2-CERK-20-GOGR 20 (40 μL) 200 μL
PACSIN2-CERK-20-GOAQ 20 (40 μL) 200 μL
PACSIN2-CERK-20-GRRE 20 (40 μL) 200 μL
PACSIN2-CERK-20-GROR 20 (40 μL) 200 μL
PACSIN2-CERK-20-GRGO 20 (40 μL) 200 μL
PACSIN2-CERK-20-GRGR 20 (40 μL) 200 μL
PACSIN2-CERK-20-GRAQ 20 (40 μL) 200 μL
PACSIN2-CERK-20-AQRE 20 (40 μL) 200 μL
PACSIN2-CERK-20-AQOR 20 (40 μL) 200 μL
PACSIN2-CERK-20-AQGO 20 (40 μL) 200 μL
PACSIN2-CERK-20-AQGR 20 (40 μL) 200 μL
PACSIN2-CERK-20-AQAQ 20 (40 μL) 200 μL

PACSIN2 Gene Summary

This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Gene Name: Protein Kinase C And Casein Kinase Substrate In Neurons 2

Chromosome: CHR22: 43265771 -43411184

Locus: 22q13.2

CERK Gene Summary

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]

Gene Name: Ceramide Kinase

Chromosome: CHR22: 47080306 -47134152

Locus: 22q13.31

Gene Diseases

The PACSIN2 CERK Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.