PABPC1-VPS13B Fusion FISH Probe
The PABPC1-VPS13B Fusion FISH Probe is used to confirm a fusion of the PABPC1 and VPS13B genes. The fusion of the PABPC1 and VPS13B genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PABPC1-VPS13B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-RERE | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-REOR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-REGO | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-REGR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-REAQ | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-ORRE | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-OROR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-ORGO | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GORE | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GOOR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GOGO | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GOGR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GRRE | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GROR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GRGO | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GRGR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-AQRE | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-AQOR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-AQGO | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-AQGR | 20 (40 μL) | 200 μL |
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| PABPC1-VPS13B-20-AQAQ | 20 (40 μL) | 200 μL |
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PABPC1 Gene Summary
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
Gene Name: Poly(A) Binding Protein Cytoplasmic 1
Chromosome: CHR8: 101715143 -101734315
Locus: 8q22.3
VPS13B Gene Summary
This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Vacuolar Protein Sorting 13 Homolog B
Chromosome: CHR8: 100025493 -100889808
Locus: 8q22.2
Gene Diseases
The PABPC1 VPS13B Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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