PA2G4-RAB5B Fusion FISH Probe
The PA2G4-RAB5B Fusion FISH Probe is used to confirm a fusion of the PA2G4 and RAB5B genes. The fusion of the PA2G4 and RAB5B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PA2G4-RAB5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-RERE | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-REOR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-REGO | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-REGR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-REAQ | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-ORRE | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-OROR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-ORGO | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GORE | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GOOR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GOGO | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GOGR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GRRE | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GROR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GRGO | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GRGR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-AQRE | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-AQOR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-AQGO | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-AQGR | 20 (40 μL) | 200 μL |
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| PA2G4-RAB5B-20-AQAQ | 20 (40 μL) | 200 μL |
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PA2G4 Gene Summary
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Proliferation-associated 2G4
Chromosome: CHR12: 56498102 -56507694
Locus: 12q13.2
RAB5B Gene Summary
The RAB5B, Member RAS Oncogene Family (RAB5B) gene is located on chr12 :56367861-56388488 at 12q13.2.
Gene Name: RAB5B, Member RAS Oncogene Family
Chromosome: CHR12: 56367861 -56388488
Locus: 12q13.2
Gene Diseases
The PA2G4 RAB5B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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