PA2G4-MARK1 Fusion FISH Probe
The PA2G4-MARK1 Fusion FISH Probe is used to confirm a fusion of the PA2G4 and MARK1 genes. The fusion of the PA2G4 and MARK1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PA2G4-MARK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-RERE | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-REOR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-REGO | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-REGR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-REAQ | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-ORRE | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-OROR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-ORGO | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GORE | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GOOR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GOGO | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GOGR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GRRE | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GROR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GRGO | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GRGR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-AQRE | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-AQOR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-AQGO | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-AQGR | 20 (40 μL) | 200 μL |
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| PA2G4-MARK1-20-AQAQ | 20 (40 μL) | 200 μL |
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MARK1 Gene Summary
The Microtubule Affinity Regulating Kinase 1 (MARK1) gene is located on chr1 :220701567-220837799 at 1q41.
Gene Name: Microtubule Affinity Regulating Kinase 1
Chromosome: CHR1: 220701567 -220837799
Locus: 1q41
PA2G4 Gene Summary
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Proliferation-associated 2G4
Chromosome: CHR12: 56498102 -56507694
Locus: 12q13.2
Gene Diseases
The PA2G4 MARK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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