P4HB-ZNFX1 Fusion FISH Probe
The P4HB-ZNFX1 Fusion FISH Probe is used to confirm a fusion of the P4HB and ZNFX1 genes. The fusion of the P4HB and ZNFX1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| P4HB-ZNFX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-RERE | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-REOR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-REGO | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-REGR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-REAQ | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-ORRE | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-OROR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-ORGO | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GORE | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GOOR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GOGO | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GOGR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GRRE | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GROR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GRGO | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GRGR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-AQRE | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-AQOR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-AQGO | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-AQGR | 20 (40 μL) | 200 μL |
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| P4HB-ZNFX1-20-AQAQ | 20 (40 μL) | 200 μL |
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P4HB Gene Summary
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl 4-hydroxylase Subunit Beta
Chromosome: CHR17: 79801033 -79818544
Locus: 17q25.3
ZNFX1 Gene Summary
The Zinc Finger NFX1-type Containing 1 (ZNFX1) gene is located on chr20 :47862438-47894756 at 20q13.13.
Gene Name: Zinc Finger NFX1-type Containing 1
Chromosome: CHR20: 47862438 -47894756
Locus: 20q13.13
Gene Diseases
The P4HB ZNFX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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