P4HB-CSDA Fusion FISH Probe
The P4HB-CSDA Fusion FISH Probe is used to confirm a fusion of the P4HB and CSDA genes. The fusion of the P4HB and CSDA genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| P4HB-CSDA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-RERE | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-REOR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-REGO | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-REGR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-REAQ | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-ORRE | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-OROR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-ORGO | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-ORAQ | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GORE | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GOOR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GOGO | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GOGR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GOAQ | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GRRE | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GROR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GRGO | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GRGR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-GRAQ | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-AQRE | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-AQOR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-AQGO | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-AQGR | 20 (40 μL) | 200 μL |
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| P4HB-CSDA-20-AQAQ | 20 (40 μL) | 200 μL |
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P4HB Gene Summary
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl 4-hydroxylase Subunit Beta
Chromosome: CHR17: 79801033 -79818544
Locus: 17q25.3
Gene Diseases
The P4HB CSDA Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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