P4HA1-CTNNA3 Fusion FISH Probe
The P4HA1-CTNNA3 Fusion FISH Probe is used to confirm a fusion of the P4HA1 and CTNNA3 genes. The fusion of the P4HA1 and CTNNA3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| P4HA1-CTNNA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-RERE | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-REOR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-REGO | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-REGR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-REAQ | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-ORRE | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-OROR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-ORGO | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GORE | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GOOR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GOGO | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GOGR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GRRE | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GROR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GRGO | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GRGR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-AQRE | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-AQOR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-AQGO | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-AQGR | 20 (40 μL) | 200 μL |
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| P4HA1-CTNNA3-20-AQAQ | 20 (40 μL) | 200 μL |
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P4HA1 Gene Summary
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl 4-hydroxylase Subunit Alpha 1
Chromosome: CHR10: 74766979 -74856732
Locus: 10q22.1
CTNNA3 Gene Summary
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Catenin Alpha 3
Chromosome: CHR10: 67679724 -69455949
Locus: 10q21.3
Gene Diseases
The P4HA1 CTNNA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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