OXSR1-PDCD6IP Fusion FISH Probe
The OXSR1-PDCD6IP Fusion FISH Probe is used to confirm a fusion of the OXSR1 and PDCD6IP genes. The fusion of the OXSR1 and PDCD6IP genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OXSR1-PDCD6IP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-RERE | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-REOR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-REGO | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-REGR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-REAQ | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-ORRE | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-OROR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-ORGO | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-ORAQ | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GORE | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GOOR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GOGO | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GOGR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GOAQ | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GRRE | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GROR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GRGO | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GRGR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-GRAQ | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-AQRE | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-AQOR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-AQGO | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-AQGR | 20 (40 μL) | 200 μL |
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| OXSR1-PDCD6IP-20-AQAQ | 20 (40 μL) | 200 μL |
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OXSR1 Gene Summary
The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Gene Name: Oxidative Stress Responsive 1
Chromosome: CHR3: 38207025 -38296979
Locus: 3p22.2
PDCD6IP Gene Summary
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
Gene Name: Programmed Cell Death 6 Interacting Protein
Chromosome: CHR3: 33840065 -33911195
Locus: 3p22.3
Gene Diseases
The OXSR1 PDCD6IP Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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