OTUB1-SUV420H1 Fusion FISH Probe
The OTUB1-SUV420H1 Fusion FISH Probe is used to confirm a fusion of the OTUB1 and SUV420H1 genes. The fusion of the OTUB1 and SUV420H1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OTUB1-SUV420H1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-RERE | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-REOR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-REGO | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-REGR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-REAQ | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-ORRE | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-OROR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-ORGO | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-ORAQ | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GORE | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GOOR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GOGO | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GOGR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GOAQ | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GRRE | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GROR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GRGO | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GRGR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-GRAQ | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-AQRE | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-AQOR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-AQGO | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-AQGR | 20 (40 μL) | 200 μL |
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| OTUB1-SUV420H1-20-AQAQ | 20 (40 μL) | 200 μL |
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OTUB1 Gene Summary
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: OTU Deubiquitinase, Ubiquitin Aldehyde Binding 1
Chromosome: CHR11: 63753324 -63765892
Locus: 11q13.1
Gene Diseases
The OTUB1 SUV420H1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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