OSBPL9-FKBP5 Fusion FISH Probe
The OSBPL9-FKBP5 Fusion FISH Probe is used to confirm a fusion of the OSBPL9 and FKBP5 genes. The fusion of the OSBPL9 and FKBP5 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBPL9-FKBP5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-RERE | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-REOR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-REGO | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-REGR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-OROR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GORE | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GROR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBPL9-FKBP5-20-AQAQ | 20 (40 μL) | 200 μL |
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FKBP5 Gene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Gene Name: FK506 Binding Protein 5
Chromosome: CHR6: 35541361 -35696360
Locus: 6p21.31
OSBPL9 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]
Gene Name: Oxysterol Binding Protein Like 9
Chromosome: CHR1: 52082545 -52254891
Locus: 1p32.3
Gene Diseases
The OSBPL9 FKBP5 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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