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OSBPL8-SYT1 Fusion FISH Probe

The OSBPL8-SYT1 Fusion FISH Probe is used to confirm a fusion of the OSBPL8 and SYT1 genes. The fusion of the OSBPL8 and SYT1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
OSBPL8-SYT1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
OSBPL8-SYT1-20-RERE 20 (40 μL) 200 μL
OSBPL8-SYT1-20-REOR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-REGO 20 (40 μL) 200 μL
OSBPL8-SYT1-20-REGR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-REAQ 20 (40 μL) 200 μL
OSBPL8-SYT1-20-ORRE 20 (40 μL) 200 μL
OSBPL8-SYT1-20-OROR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-ORGO 20 (40 μL) 200 μL
OSBPL8-SYT1-20-ORAQ 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GORE 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GOOR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GOGO 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GOGR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GOAQ 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GRRE 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GROR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GRGO 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GRGR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-GRAQ 20 (40 μL) 200 μL
OSBPL8-SYT1-20-AQRE 20 (40 μL) 200 μL
OSBPL8-SYT1-20-AQOR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-AQGO 20 (40 μL) 200 μL
OSBPL8-SYT1-20-AQGR 20 (40 μL) 200 μL
OSBPL8-SYT1-20-AQAQ 20 (40 μL) 200 μL

SYT1 Gene Summary

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]

Gene Name: Synaptotagmin 1

Chromosome: CHR12: 79257772 -79845788

Locus: 12q21.2

OSBPL8 Gene Summary

This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Gene Name: Oxysterol Binding Protein Like 8

Chromosome: CHR12: 76745577 -76953589

Locus: 12q21.2

Gene Diseases

The OSBPL8 SYT1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.