OSBPL8-NTS Fusion FISH Probe
The OSBPL8-NTS Fusion FISH Probe is used to confirm a fusion of the OSBPL8 and NTS genes. The fusion of the OSBPL8 and NTS genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBPL8-NTS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-RERE | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-REOR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-REGO | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-REGR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-OROR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GORE | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GROR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBPL8-NTS-20-AQAQ | 20 (40 μL) | 200 μL |
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NTS Gene Summary
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]
Gene Name: Neurotensin
Chromosome: CHR12: 86268072 -86276770
Locus: 12q21.31
OSBPL8 Gene Summary
This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Oxysterol Binding Protein Like 8
Chromosome: CHR12: 76745577 -76953589
Locus: 12q21.2
Gene Diseases
The OSBPL8 NTS Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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