OSBPL2-DLGAP4 Fusion FISH Probe
The OSBPL2-DLGAP4 Fusion FISH Probe is used to confirm a fusion of the OSBPL2 and DLGAP4 genes. The fusion of the OSBPL2 and DLGAP4 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBPL2-DLGAP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-RERE | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-REOR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-REGO | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-REGR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-OROR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GORE | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GROR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBPL2-DLGAP4-20-AQAQ | 20 (40 μL) | 200 μL |
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OSBPL2 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
Gene Name: Oxysterol Binding Protein Like 2
Chromosome: CHR20: 60813579 -60871269
Locus: 20q13.33
DLGAP4 Gene Summary
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: DLG Associated Protein 4
Chromosome: CHR20: 34995443 -35157040
Locus: 20q11.23
Gene Diseases
The OSBPL2 DLGAP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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