OSBPL1A-RIOK3 Fusion FISH Probe
The OSBPL1A-RIOK3 Fusion FISH Probe is used to confirm a fusion of the OSBPL1A and RIOK3 genes. The fusion of the OSBPL1A and RIOK3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBPL1A-RIOK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-RERE | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-REOR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-REGO | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-REGR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-OROR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GORE | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GROR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBPL1A-RIOK3-20-AQAQ | 20 (40 μL) | 200 μL |
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RIOK3 Gene Summary
This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that localizes to the cytoplasm and plays a role in the processing of the pre-40 S ribosomal subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]
Gene Name: RIO Kinase 3
Chromosome: CHR18: 21032786 -21063099
Locus: 18q11.2
OSBPL1A Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Oxysterol Binding Protein Like 1A
Chromosome: CHR18: 21742010 -21977833
Locus: 18q11.2
Gene Diseases
The OSBPL1A RIOK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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