OSBPL10-GPD1L Fusion FISH Probe
The OSBPL10-GPD1L Fusion FISH Probe is used to confirm a fusion of the OSBPL10 and GPD1L genes. The fusion of the OSBPL10 and GPD1L genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBPL10-GPD1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-RERE | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-REOR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-REGO | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-REGR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-OROR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GORE | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GROR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBPL10-GPD1L-20-AQAQ | 20 (40 μL) | 200 μL |
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GPD1L Gene Summary
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
Gene Name: Glycerol-3-phosphate Dehydrogenase 1 Like
Chromosome: CHR3: 32148002 -32210207
Locus: 3p22.3
OSBPL10 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Name: Oxysterol Binding Protein Like 10
Chromosome: CHR3: 31702316 -32023342
Locus: 3p23
Gene Diseases
The OSBPL10 GPD1L Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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