OSBP2-TST Fusion FISH Probe
The OSBP2-TST Fusion FISH Probe is used to confirm a fusion of the OSBP2 and TST genes. The fusion of the OSBP2 and TST genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBP2-TST-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-RERE | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-REOR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-REGO | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-REGR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-OROR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GORE | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GROR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBP2-TST-20-AQAQ | 20 (40 μL) | 200 μL |
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TST Gene Summary
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Name: Thiosulfate Sulfurtransferase
Chromosome: CHR22: 37406905 -37415491
Locus: 22q12.3
OSBP2 Gene Summary
The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Oxysterol Binding Protein 2
Chromosome: CHR22: 31090792 -31303811
Locus: 22q12.2
Gene Diseases
The OSBP2 TST Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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