OSBP-GIF Fusion FISH Probe
The OSBP-GIF Fusion FISH Probe is used to confirm a fusion of the OSBP and GIF genes. The fusion of the OSBP and GIF genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OSBP-GIF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-RERE | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-REOR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-REGO | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-REGR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-REAQ | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-ORRE | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-OROR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-ORGO | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-ORAQ | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GORE | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GOOR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GOGO | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GOGR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GOAQ | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GRRE | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GROR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GRGO | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GRGR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-GRAQ | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-AQRE | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-AQOR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-AQGO | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-AQGR | 20 (40 μL) | 200 μL |
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| OSBP-GIF-20-AQAQ | 20 (40 μL) | 200 μL |
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GIF Gene Summary
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008]
Gene Name: Gastric Intrinsic Factor
Chromosome: CHR11: 59596745 -59612974
Locus: 11q12.1
OSBP Gene Summary
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008]
Gene Name: Oxysterol Binding Protein
Chromosome: CHR11: 59341870 -59383617
Locus: 11q12.1
Gene Diseases
The OSBP GIF Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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