OPA1-PIGX Fusion FISH Probe
The OPA1-PIGX Fusion FISH Probe is used to confirm a fusion of the OPA1 and PIGX genes. The fusion of the OPA1 and PIGX genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OPA1-PIGX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-RERE | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-REOR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-REGO | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-REGR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-REAQ | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-ORRE | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-OROR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-ORGO | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-ORAQ | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GORE | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GOOR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GOGO | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GOGR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GOAQ | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GRRE | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GROR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GRGO | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GRGR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-GRAQ | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-AQRE | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-AQOR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-AQGO | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-AQGR | 20 (40 μL) | 200 μL |
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| OPA1-PIGX-20-AQAQ | 20 (40 μL) | 200 μL |
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OPA1 Gene Summary
The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]
Gene Name: OPA1, Mitochondrial Dynamin Like GTPase
Chromosome: CHR3: 193310932 -193415600
Locus: 3q29
PIGX Gene Summary
This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class X
Chromosome: CHR3: 196439244 -196462876
Locus: 3q29
Gene Diseases
The OPA1 PIGX Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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