OGT-POLA1 Fusion FISH Probe
The OGT-POLA1 Fusion FISH Probe is used to confirm a fusion of the OGT and POLA1 genes. The fusion of the OGT and POLA1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OGT-POLA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-RERE | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-REOR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-REGO | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-REGR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-REAQ | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-ORRE | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-OROR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-ORGO | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GORE | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GOOR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GOGO | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GOGR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GRRE | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GROR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GRGO | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GRGR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-AQRE | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-AQOR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-AQGO | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-AQGR | 20 (40 μL) | 200 μL |
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| OGT-POLA1-20-AQAQ | 20 (40 μL) | 200 μL |
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POLA1 Gene Summary
This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication. [provided by RefSeq, Mar 2010]
Gene Name: DNA Polymerase Alpha 1, Catalytic Subunit
Chromosome: CHRX: 24712063 -25015102
Locus: Xp22.11-p21.3
OGT Gene Summary
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: O-linked N-acetylglucosamine (GlcNAc) Transferase
Chromosome: CHRX: 70752911 -70795747
Locus: Xq13.1
Gene Diseases
The OGT POLA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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