OCLN-CCNB1 Fusion FISH Probe
The OCLN-CCNB1 Fusion FISH Probe is used to confirm a fusion of the OCLN and CCNB1 genes. The fusion of the OCLN and CCNB1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OCLN-CCNB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-RERE | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-REOR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-REGO | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-REGR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-REAQ | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-ORRE | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-OROR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-ORGO | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GORE | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GOOR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GOGO | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GOGR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GRRE | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GROR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GRGO | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GRGR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-AQRE | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-AQOR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-AQGO | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-AQGR | 20 (40 μL) | 200 μL |
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| OCLN-CCNB1-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNB1 Gene Summary
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary for proper control of the G2/M transition phase of the cell cycle. [provided by RefSeq, Aug 2017]
Gene Name: Cyclin B1
Chromosome: CHR5: 68462912 -68474070
Locus: 5q13.2
OCLN Gene Summary
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Gene Name: Occludin
Chromosome: CHR5: 68788118 -68853931
Locus: 5q13.2
Gene Diseases
The OCLN CCNB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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