NVL-WDR26 Fusion FISH Probe
The NVL-WDR26 Fusion FISH Probe is used to confirm a fusion of the NVL and WDR26 genes. The fusion of the NVL and WDR26 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NVL-WDR26-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-RERE | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-REOR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-REGO | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-REGR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-REAQ | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-ORRE | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-OROR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-ORGO | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-ORAQ | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GORE | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GOOR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GOGO | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GOGR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GOAQ | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GRRE | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GROR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GRGO | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GRGR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-GRAQ | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-AQRE | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-AQOR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-AQGO | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-AQGR | 20 (40 μL) | 200 μL |
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| NVL-WDR26-20-AQAQ | 20 (40 μL) | 200 μL |
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NVL Gene Summary
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011]
Gene Name: Nuclear VCP-like
Chromosome: CHR1: 224415035 -224517891
Locus: 1q42.11
WDR26 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 26
Chromosome: CHR1: 224572844 -224622001
Locus: 1q42.11-q42.12
Gene Diseases
The NVL WDR26 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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