NVL-LARS2 Fusion FISH Probe
The NVL-LARS2 Fusion FISH Probe is used to confirm a fusion of the NVL and LARS2 genes. The fusion of the NVL and LARS2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NVL-LARS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-RERE | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-REOR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-REGO | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-REGR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-REAQ | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-ORRE | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-OROR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-ORGO | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GORE | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GOOR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GOGO | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GOGR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GRRE | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GROR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GRGO | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GRGR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-AQRE | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-AQOR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-AQGO | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-AQGR | 20 (40 μL) | 200 μL |
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| NVL-LARS2-20-AQAQ | 20 (40 μL) | 200 μL |
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NVL Gene Summary
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011]
Gene Name: Nuclear VCP-like
Chromosome: CHR1: 224415035 -224517891
Locus: 1q42.11
LARS2 Gene Summary
This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]
Gene Name: Leucyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR3: 45430074 -45590328
Locus: 3p21.31
Gene Diseases
The NVL LARS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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