NUPL1-KL Fusion FISH Probe
The NUPL1-KL Fusion FISH Probe is used to confirm a fusion of the NUPL1 and KL genes. The fusion of the NUPL1 and KL genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUPL1-KL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-RERE | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-REOR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-REGO | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-REGR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-REAQ | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-ORRE | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-OROR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-ORGO | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GORE | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GOOR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GOGO | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GOGR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GRRE | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GROR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GRGO | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GRGR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-AQRE | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-AQOR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-AQGO | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-AQGR | 20 (40 μL) | 200 μL |
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| NUPL1-KL-20-AQAQ | 20 (40 μL) | 200 μL |
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KL Gene Summary
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]
Gene Name: Klotho
Chromosome: CHR13: 33590570 -33640282
Locus: 13q13.1
Gene Diseases
The NUPL1 KL Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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