NUP214-AIF1L Fusion FISH Probe
The NUP214-AIF1L Fusion FISH Probe is used to confirm a fusion of the NUP214 and AIF1L genes. The fusion of the NUP214 and AIF1L genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP214-AIF1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-RERE | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-REOR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-REGO | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-REGR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-OROR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GORE | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GROR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP214-AIF1L-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP214 Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: Nucleoporin 214
Chromosome: CHR9: 134000980 -134109091
Locus: 9q34.13
AIF1L Gene Summary
The Allograft Inflammatory Factor 1 Like (AIF1L) gene is located on chr9 :133971862-133998539 at 9q34.12-q34.13.
Gene Name: Allograft Inflammatory Factor 1 Like
Chromosome: CHR9: 133971862 -133998539
Locus: 9q34.12-q34.13
Gene Diseases
The NUP214 AIF1L Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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