NUP188-TMEM8C Fusion FISH Probe
The NUP188-TMEM8C Fusion FISH Probe is used to confirm a fusion of the NUP188 and TMEM8C genes. The fusion of the NUP188 and TMEM8C genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP188-TMEM8C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-RERE | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-REOR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-REGO | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-REGR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-OROR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GORE | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GROR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP188-TMEM8C-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP188 Gene Summary
The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013]
Gene Name: Nucleoporin 188
Chromosome: CHR9: 131709976 -131769374
Locus: 9q34.11
Gene Diseases
The NUP188 TMEM8C Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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