NUP155-TRIO Fusion FISH Probe
The NUP155-TRIO Fusion FISH Probe is used to confirm a fusion of the NUP155 and TRIO genes. The fusion of the NUP155 and TRIO genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP155-TRIO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-RERE | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-REOR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-REGO | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-REGR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-OROR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GORE | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GROR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP155-TRIO-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
NUP155 Gene Summary
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]
Gene Name: Nucleoporin 155
Chromosome: CHR5: 37291940 -37371197
Locus: 5p13.2
Gene Diseases
The NUP155 TRIO Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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