NUMA1-FOXP1 Fusion FISH Probe
The NUMA1-FOXP1 Fusion FISH Probe is used to confirm a fusion of the NUMA1 and FOXP1 genes. The fusion of the NUMA1 and FOXP1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUMA1-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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NUMA1 Gene Summary
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: Nuclear Mitotic Apparatus Protein 1
Chromosome: CHR11: 71713910 -71791573
Locus: 11q13.4
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The NUMA1 FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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