NUMA1-CRYM Fusion FISH Probe
The NUMA1-CRYM Fusion FISH Probe is used to confirm a fusion of the NUMA1 and CRYM genes. The fusion of the NUMA1 and CRYM genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUMA1-CRYM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-RERE | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-REOR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-REGO | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-REGR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-REAQ | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-ORRE | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-OROR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-ORGO | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GORE | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GOOR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GOGO | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GOGR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GRRE | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GROR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GRGO | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GRGR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-AQRE | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-AQOR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-AQGO | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-AQGR | 20 (40 μL) | 200 μL |
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| NUMA1-CRYM-20-AQAQ | 20 (40 μL) | 200 μL |
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CRYM Gene Summary
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]
Gene Name: Crystallin Mu
Chromosome: CHR16: 21269838 -21314404
Locus: 16p12.2
NUMA1 Gene Summary
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: Nuclear Mitotic Apparatus Protein 1
Chromosome: CHR11: 71713910 -71791573
Locus: 11q13.4
Gene Diseases
The NUMA1 CRYM Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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