NUMA1-ABHD12 Fusion FISH Probe
The NUMA1-ABHD12 Fusion FISH Probe is used to confirm a fusion of the NUMA1 and ABHD12 genes. The fusion of the NUMA1 and ABHD12 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUMA1-ABHD12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-RERE | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-REOR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-REGO | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-REGR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-REAQ | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-ORRE | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-OROR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-ORGO | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GORE | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GOOR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GOGO | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GOGR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GRRE | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GROR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GRGO | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GRGR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-AQRE | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-AQOR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-AQGO | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-AQGR | 20 (40 μL) | 200 μL |
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| NUMA1-ABHD12-20-AQAQ | 20 (40 μL) | 200 μL |
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NUMA1 Gene Summary
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: Nuclear Mitotic Apparatus Protein 1
Chromosome: CHR11: 71713910 -71791573
Locus: 11q13.4
ABHD12 Gene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
Gene Name: Abhydrolase Domain Containing 12
Chromosome: CHR20: 25275378 -25371618
Locus: 20p11.21
Gene Diseases
The NUMA1 ABHD12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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