NUDT4-ADD1 Fusion FISH Probe
The NUDT4-ADD1 Fusion FISH Probe is used to confirm a fusion of the NUDT4 and ADD1 genes. The fusion of the NUDT4 and ADD1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUDT4-ADD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-RERE | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-REOR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-REGO | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-REGR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-REAQ | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-ORRE | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-OROR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-ORGO | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GORE | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GOOR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GOGO | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GOGR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GRRE | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GROR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GRGO | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GRGR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-AQRE | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-AQOR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-AQGO | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-AQGR | 20 (40 μL) | 200 μL |
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| NUDT4-ADD1-20-AQAQ | 20 (40 μL) | 200 μL |
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ADD1 Gene Summary
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
Gene Name: Adducin 1
Chromosome: CHR4: 2845583 -2931802
Locus: 4p16.3
NUDT4 Gene Summary
The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008]
Gene Name: Nudix Hydrolase 4
Chromosome: CHR12: 93771700 -93797024
Locus: 12q22
Gene Diseases
The NUDT4 ADD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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