NUDT3-DNAH8 Fusion FISH Probe
The NUDT3-DNAH8 Fusion FISH Probe is used to confirm a fusion of the NUDT3 and DNAH8 genes. The fusion of the NUDT3 and DNAH8 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUDT3-DNAH8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-RERE | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-REOR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-REGO | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-REGR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-REAQ | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-ORRE | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-OROR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-ORGO | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GORE | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GOOR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GOGO | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GOGR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GRRE | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GROR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GRGO | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GRGR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-AQRE | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-AQOR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-AQGO | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-AQGR | 20 (40 μL) | 200 μL |
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| NUDT3-DNAH8-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAH8 Gene Summary
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]
Gene Name: Dynein Axonemal Heavy Chain 8
Chromosome: CHR6: 38683116 -38998574
Locus: 6p21.2
NUDT3 Gene Summary
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM, Feb 2011]
Gene Name: Nudix Hydrolase 3
Chromosome: CHR6: 34254972 -34360457
Locus: 6p21.31
Gene Diseases
The NUDT3 DNAH8 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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