NUCKS1-SDCCAG8 Fusion FISH Probe
The NUCKS1-SDCCAG8 Fusion FISH Probe is used to confirm a fusion of the NUCKS1 and SDCCAG8 genes. The fusion of the NUCKS1 and SDCCAG8 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUCKS1-SDCCAG8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-RERE | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-REOR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-REGO | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-REGR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-REAQ | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-ORRE | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-OROR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-ORGO | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GORE | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GOOR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GOGO | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GOGR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GRRE | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GROR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GRGO | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GRGR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-AQRE | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-AQOR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-AQGO | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-AQGR | 20 (40 μL) | 200 μL |
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| NUCKS1-SDCCAG8-20-AQAQ | 20 (40 μL) | 200 μL |
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SDCCAG8 Gene Summary
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]
Gene Name: Serologically Defined Colon Cancer Antigen 8
Chromosome: CHR1: 243419306 -243663393
Locus: 1q43-q44
NUCKS1 Gene Summary
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010]
Gene Name: Nuclear Casein Kinase And Cyclin Dependent Kinase Substrate 1
Chromosome: CHR1: 205681946 -205719372
Locus: 1q32.1
Gene Diseases
The NUCKS1 SDCCAG8 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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