NTRK1-DYNC2H1 Fusion FISH Probe
The NTRK1-DYNC2H1 Fusion FISH Probe is used to confirm a fusion of the NTRK1 and DYNC2H1 genes. The fusion of the NTRK1 and DYNC2H1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NTRK1-DYNC2H1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-RERE | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-REOR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-REGO | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-REGR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-REAQ | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-ORRE | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-OROR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-ORGO | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GORE | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GOOR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GOGO | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GOGR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GRRE | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GROR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GRGO | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GRGR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-AQRE | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-AQOR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-AQGO | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-AQGR | 20 (40 μL) | 200 μL |
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| NTRK1-DYNC2H1-20-AQAQ | 20 (40 μL) | 200 μL |
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NTRK1 Gene Summary
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Gene Name: Neurotrophic Receptor Tyrosine Kinase 1
Chromosome: CHR1: 156785541 -156851642
Locus: 1q23.1
DYNC2H1 Gene Summary
This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
Gene Name: Dynein Cytoplasmic 2 Heavy Chain 1
Chromosome: CHR11: 102980159 -103350591
Locus: 11q22.3
Gene Diseases
The NTRK1 DYNC2H1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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