NTN4-KIFAP3 Fusion FISH Probe
The NTN4-KIFAP3 Fusion FISH Probe is used to confirm a fusion of the NTN4 and KIFAP3 genes. The fusion of the NTN4 and KIFAP3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NTN4-KIFAP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-RERE | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-REOR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-REGO | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-REGR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-REAQ | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-ORRE | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-OROR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-ORGO | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GORE | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GOOR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GOGO | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GOGR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GRRE | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GROR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GRGO | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GRGR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-AQRE | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-AQOR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-AQGO | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-AQGR | 20 (40 μL) | 200 μL |
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| NTN4-KIFAP3-20-AQAQ | 20 (40 μL) | 200 μL |
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KIFAP3 Gene Summary
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: Kinesin Associated Protein 3
Chromosome: CHR1: 169890469 -170043879
Locus: 1q24.2
NTN4 Gene Summary
This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Gene Name: Netrin 4
Chromosome: CHR12: 96051582 -96184536
Locus: 12q22
Gene Diseases
The NTN4 KIFAP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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