NTM-SORL1 Fusion FISH Probe
The NTM-SORL1 Fusion FISH Probe is used to confirm a fusion of the NTM and SORL1 genes. The fusion of the NTM and SORL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NTM-SORL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-RERE | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-REOR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-REGO | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-REGR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-REAQ | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-ORRE | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-OROR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-ORGO | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GORE | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GOOR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GOGO | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GOGR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GRRE | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GROR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GRGO | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GRGR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-AQRE | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-AQOR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-AQGO | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-AQGR | 20 (40 μL) | 200 μL |
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| NTM-SORL1-20-AQAQ | 20 (40 μL) | 200 μL |
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SORL1 Gene Summary
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016]
Gene Name: Sortilin Related Receptor 1
Chromosome: CHR11: 121322911 -121504471
Locus: 11q24.1
NTM Gene Summary
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
Gene Name: Neurotrimin
Chromosome: CHR11: 131240370 -132206716
Locus: 11q25
Gene Diseases
The NTM SORL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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