NT5DC1-SEC63 Fusion FISH Probe
The NT5DC1-SEC63 Fusion FISH Probe is used to confirm a fusion of the NT5DC1 and SEC63 genes. The fusion of the NT5DC1 and SEC63 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NT5DC1-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-RERE | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-REOR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-REGO | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-REGR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-OROR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GORE | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GROR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
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| NT5DC1-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
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SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
NT5DC1 Gene Summary
While the exact function of the protein encoded by this gene is not known, it belongs to the 5'(3')-deoxyribonucleotidase family. [provided by RefSeq, May 2010]
Gene Name: 5'-nucleotidase Domain Containing 1
Chromosome: CHR6: 116421998 -116566853
Locus: 6q22.1
Gene Diseases
The NT5DC1 SEC63 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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