NSMAF-LETM2 Fusion FISH Probe
The NSMAF-LETM2 Fusion FISH Probe is used to confirm a fusion of the NSMAF and LETM2 genes. The fusion of the NSMAF and LETM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NSMAF-LETM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-RERE | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-REOR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-REGO | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-REGR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-REAQ | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-ORRE | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-OROR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-ORGO | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GORE | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GOOR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GOGO | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GOGR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GRRE | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GROR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GRGO | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GRGR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-AQRE | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-AQOR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-AQGO | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-AQGR | 20 (40 μL) | 200 μL |
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| NSMAF-LETM2-20-AQAQ | 20 (40 μL) | 200 μL |
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NSMAF Gene Summary
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
Gene Name: Neutral Sphingomyelinase Activation Associated Factor
Chromosome: CHR8: 59496063 -59572404
Locus: 8q12.1
LETM2 Gene Summary
The Leucine Zipper And EF-hand Containing Transmembrane Protein 2 (LETM2) gene is located on chr8 :38243958-38266062 at 8p11.23.
Gene Name: Leucine Zipper And EF-hand Containing Transmembrane Protein 2
Chromosome: CHR8: 38243958 -38266062
Locus: 8p11.23
Gene Diseases
The NSMAF LETM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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