NSA2-PCDHA3 Fusion FISH Probe
The NSA2-PCDHA3 Fusion FISH Probe is used to confirm a fusion of the NSA2 and PCDHA3 genes. The fusion of the NSA2 and PCDHA3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NSA2-PCDHA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-RERE | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-REOR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-REGO | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-REGR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-REAQ | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-ORRE | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-OROR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-ORGO | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GORE | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GOOR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GOGO | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GOGR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GRRE | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GROR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GRGO | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GRGR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-AQRE | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-AQOR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-AQGO | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-AQGR | 20 (40 μL) | 200 μL |
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| NSA2-PCDHA3-20-AQAQ | 20 (40 μL) | 200 μL |
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NSA2 Gene Summary
This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]
Gene Name: NSA2, Ribosome Biogenesis Homolog
Chromosome: CHR5: 74063102 -74072734
Locus: 5q13.3
PCDHA3 Gene Summary
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Name: Protocadherin Alpha 3
Chromosome: CHR5: 140180782 -140391929
Locus: 5q31.3
Gene Diseases
The NSA2 PCDHA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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