NRP2-PARD3B Fusion FISH Probe
The NRP2-PARD3B Fusion FISH Probe is used to confirm a fusion of the NRP2 and PARD3B genes. The fusion of the NRP2 and PARD3B genes has been associated with Head And Neck Squamous Cell Carcinoma , Skin Cutaneous Melanoma, and Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NRP2-PARD3B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-RERE | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-REOR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-REGO | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-REGR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-REAQ | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-ORRE | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-OROR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-ORGO | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GORE | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GOOR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GOGO | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GOGR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GRRE | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GROR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GRGO | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GRGR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-AQRE | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-AQOR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-AQGO | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-AQGR | 20 (40 μL) | 200 μL |
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| NRP2-PARD3B-20-AQAQ | 20 (40 μL) | 200 μL |
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NRP2 Gene Summary
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Neuropilin 2
Chromosome: CHR2: 206547223 -206662857
Locus: 2q33.3
PARD3B Gene Summary
The Par-3 Family Cell Polarity Regulator Beta (PARD3B) gene is located on chr2 :205410515-206484886 at 2q33.3.
Gene Name: Par-3 Family Cell Polarity Regulator Beta
Chromosome: CHR2: 205410515 -206484886
Locus: 2q33.3
Gene Diseases
The NRP2 PARD3B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Skin Cutaneous Melanoma |
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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