NRF1-PPP2R5A Fusion FISH Probe
The NRF1-PPP2R5A Fusion FISH Probe is used to confirm a fusion of the NRF1 and PPP2R5A genes. The fusion of the NRF1 and PPP2R5A genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NRF1-PPP2R5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NRF1-PPP2R5A-20-AQAQ | 20 (40 μL) | 200 μL |
|
NRF1 Gene Summary
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]
Gene Name: Nuclear Respiratory Factor 1
Chromosome: CHR7: 129251554 -129396922
Locus: 7q32.2
PPP2R5A Gene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'alpha
Chromosome: CHR1: 212458878 -212535205
Locus: 1q32.3
Gene Diseases
The NRF1 PPP2R5A Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|