NR5A1-NR6A1 Fusion FISH Probe
The NR5A1-NR6A1 Fusion FISH Probe is used to confirm a fusion of the NR5A1 and NR6A1 genes. The fusion of the NR5A1 and NR6A1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NR5A1-NR6A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-RERE | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-REOR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-REGO | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-REGR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-REAQ | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-ORRE | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-OROR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-ORGO | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GORE | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GOOR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GOGO | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GOGR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GRRE | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GROR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GRGO | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GRGR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-AQRE | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-AQOR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-AQGO | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-AQGR | 20 (40 μL) | 200 μL |
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| NR5A1-NR6A1-20-AQAQ | 20 (40 μL) | 200 μL |
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NR5A1 Gene Summary
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Receptor Subfamily 5 Group A Member 1
Chromosome: CHR9: 127243514 -127269699
Locus: 9q33.3
NR6A1 Gene Summary
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013]
Gene Name: Nuclear Receptor Subfamily 6 Group A Member 1
Chromosome: CHR9: 127284702 -127533576
Locus: 9q33.3
Gene Diseases
The NR5A1 NR6A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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