NR4A2-GPD2 Fusion FISH Probe
The NR4A2-GPD2 Fusion FISH Probe is used to confirm a fusion of the NR4A2 and GPD2 genes. The fusion of the NR4A2 and GPD2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NR4A2-GPD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-RERE | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-REOR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-REGO | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-REGR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-REAQ | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-ORRE | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-OROR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-ORGO | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GORE | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GOOR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GOGO | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GOGR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GRRE | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GROR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GRGO | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GRGR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-AQRE | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-AQOR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-AQGO | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-AQGR | 20 (40 μL) | 200 μL |
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| NR4A2-GPD2-20-AQAQ | 20 (40 μL) | 200 μL |
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GPD2 Gene Summary
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]
Gene Name: Glycerol-3-phosphate Dehydrogenase 2
Chromosome: CHR2: 157291964 -157442915
Locus: 2q24.1
NR4A2 Gene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Receptor Subfamily 4 Group A Member 2
Chromosome: CHR2: 157180943 -157189287
Locus: 2q24.1
Gene Diseases
The NR4A2 GPD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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