NR3C2-SPATA17 Fusion FISH Probe
The NR3C2-SPATA17 Fusion FISH Probe is used to confirm a fusion of the NR3C2 and SPATA17 genes. The fusion of the NR3C2 and SPATA17 genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NR3C2-SPATA17-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-RERE | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-REOR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-REGO | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-REGR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-REAQ | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-ORRE | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-OROR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-ORGO | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-ORAQ | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GORE | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GOOR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GOGO | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GOGR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GOAQ | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GRRE | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GROR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GRGO | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GRGR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-GRAQ | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-AQRE | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-AQOR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-AQGO | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-AQGR | 20 (40 μL) | 200 μL |
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| NR3C2-SPATA17-20-AQAQ | 20 (40 μL) | 200 μL |
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NR3C2 Gene Summary
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Nuclear Receptor Subfamily 3 Group C Member 2
Chromosome: CHR4: 148999914 -149363672
Locus: 4q31.23
SPATA17 Gene Summary
The Spermatogenesis Associated 17 (SPATA17) gene is located on chr1 :217804694-218040484 at 1q41.
Gene Name: Spermatogenesis Associated 17
Chromosome: CHR1: 217804694 -218040484
Locus: 1q41
Gene Diseases
The NR3C2 SPATA17 Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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