NPY-FOXP1 Fusion FISH Probe
The NPY-FOXP1 Fusion FISH Probe is used to confirm a fusion of the NPY and FOXP1 genes. The fusion of the NPY and FOXP1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NPY-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NPY-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
NPY Gene Summary
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Gene Name: Neuropeptide Y
Chromosome: CHR7: 24323806 -24331484
Locus: 7p15.3
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The NPY FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|