NPTXR-PDXP Fusion FISH Probe
The NPTXR-PDXP Fusion FISH Probe is used to confirm a fusion of the NPTXR and PDXP genes. The fusion of the NPTXR and PDXP genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NPTXR-PDXP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-RERE | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-REOR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-REGO | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-REGR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-REAQ | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-ORRE | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-OROR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-ORGO | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-ORAQ | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GORE | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GOOR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GOGO | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GOGR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GOAQ | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GRRE | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GROR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GRGO | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GRGR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-GRAQ | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-AQRE | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-AQOR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-AQGO | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-AQGR | 20 (40 μL) | 200 μL |
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| NPTXR-PDXP-20-AQAQ | 20 (40 μL) | 200 μL |
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NPTXR Gene Summary
This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]
Gene Name: Neuronal Pentraxin Receptor
Chromosome: CHR22: 39214455 -39240017
Locus: 22q13.1
PDXP Gene Summary
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008]
Gene Name: Pyridoxal Phosphatase
Chromosome: CHR22: 38054736 -38062939
Locus: 22q13.1
Gene Diseases
The NPTXR PDXP Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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