NPLOC4-PDE6G Fusion FISH Probe
The NPLOC4-PDE6G Fusion FISH Probe is used to confirm a fusion of the NPLOC4 and PDE6G genes. The fusion of the NPLOC4 and PDE6G genes has been associated with Lung Squamous Cell Carcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NPLOC4-PDE6G-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-RERE | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-REOR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-REGO | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-REGR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-REAQ | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-ORRE | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-OROR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-ORGO | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-ORAQ | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GORE | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GOOR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GOGO | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GOGR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GOAQ | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GRRE | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GROR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GRGO | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GRGR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-GRAQ | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-AQRE | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-AQOR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-AQGO | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-AQGR | 20 (40 μL) | 200 μL |
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| NPLOC4-PDE6G-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE6G Gene Summary
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Gene Name: Phosphodiesterase 6G
Chromosome: CHR17: 79617488 -79623607
Locus: 17q25.3
NPLOC4 Gene Summary
The NPL4 Homolog, Ubiquitin Recognition Factor (NPLOC4) gene is located on chr17 :79523912-79604138 at 17q25.3.
Gene Name: NPL4 Homolog, Ubiquitin Recognition Factor
Chromosome: CHR17: 79523912 -79604138
Locus: 17q25.3
Gene Diseases
The NPLOC4 PDE6G Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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