NPHP4-ACOT7 Fusion FISH Probe
The NPHP4-ACOT7 Fusion FISH Probe is used to confirm a fusion of the NPHP4 and ACOT7 genes. The fusion of the NPHP4 and ACOT7 genes has been associated with Brain Lower Grade Glioma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NPHP4-ACOT7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-RERE | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-REOR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-REGO | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-REGR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-REAQ | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-ORRE | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-OROR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-ORGO | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-ORAQ | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GORE | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GOOR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GOGO | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GOGR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GOAQ | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GRRE | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GROR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GRGO | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GRGR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-GRAQ | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-AQRE | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-AQOR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-AQGO | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-AQGR | 20 (40 μL) | 200 μL |
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| NPHP4-ACOT7-20-AQAQ | 20 (40 μL) | 200 μL |
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ACOT7 Gene Summary
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Thioesterase 7
Chromosome: CHR1: 6324331 -6453826
Locus: 1p36.31
NPHP4 Gene Summary
This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Nephrocystin 4
Chromosome: CHR1: 5922869 -6052533
Locus: 1p36.31
Gene Diseases
The NPHP4 ACOT7 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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