NOV-ENPP2 Fusion FISH Probe
The NOV-ENPP2 Fusion FISH Probe is used to confirm a fusion of the NOV and ENPP2 genes. The fusion of the NOV and ENPP2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOV-ENPP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-RERE | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-REOR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-REGO | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-REGR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-REAQ | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-ORRE | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-OROR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-ORGO | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GORE | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GOOR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GOGO | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GOGR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GRRE | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GROR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GRGO | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GRGR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-AQRE | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-AQOR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-AQGO | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-AQGR | 20 (40 μL) | 200 μL |
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| NOV-ENPP2-20-AQAQ | 20 (40 μL) | 200 μL |
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NOV Gene Summary
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]
Gene Name: Nephroblastoma Overexpressed
Chromosome: CHR8: 120428551 -120436678
Locus: 8q24.12
ENPP2 Gene Summary
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
Gene Name: Ectonucleotide Pyrophosphatase/phosphodiesterase 2
Chromosome: CHR8: 120569318 -120651106
Locus: 8q24.12
Gene Diseases
The NOV ENPP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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